Zbot, a virus made by criminals, is still alive and well on the internet. Designed to steal confidential information, this virus can steal your banking information and more. Below is an USB drive that is infected with multiple viruses including Zbot.
Always make sure AutoPlay is off on your computer and have multiple virus removal tools. You should also have a sacrificial Tools USB drive that contains tools such as Malwarebytes, Adwcleaner, SuperAntiSpyware, RKill, RogueKiller, ComboFix and others.
Your USB should be scanned in a virtual machine after use. The example below is from an USB drive that was used to remove viruses from an infected computer. As you can see the drive contained multiple infections from different viruses.
You will also want to have a duplicate VM so the one you clean viruses with can be deleted and a new copy of the VM loaded.